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Non-Steroidal Anti-inflammatory Drugs In some patients, the administration of non-steroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. Because of the potential fall in blood pressure in these patients, therapy should be started under very close medical supervision. Removal of zestoretic non prescrizione angiotensin II negative feedback on renin secretion leads to increased plasma renin activity. These tests may be used to monitor your condition or check for side effects. Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient. Low Sodium Diet May increase risk of high blood levels of potassium. It is combination of two medicines: Zestril lisinopril and hydrochlorothiazide.